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There are many theories regarding the causes of Vitiligo and the process through which this disease spreads, however studies have demonstrated that the loss of cutaneous melanocytes can be caused by decreased circulating and lesional skin levels of the naturally occurring melanocortin peptide hormone, alpha-melanocyte (-MSH)

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Physically, the mucusciliary clearance system continuously removes mucus-encased microbes toward the pharynx 113

However, it is generally more challenging for vegans and vegetarians to obtain adequate B12 solely from plant-based sources

Slower clearance in women, a smaller apparent volume of distribution (adjusted for weight), and higher absolute bioavailability resulted in higher plasma ondansetron concentrations