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It is an unapproved drug and cannot be legally prescribed or sold over the counter, according to Operation Supplement Safety, a Department of Defense educational project

Frequently asked questions about Milk Thistle People with allergies to composite flowers, as well as pregnant women, nursing mothers, or people taking medication, should consult their doctor before taking products containing milk thistle

Liver Use with Caution Use with caution in individuals with liver conditions

De Silva A, Bloom SR

Favorable changes of some immune system parameters, particularly an increase in regulator T cells, were observed and gut microbiome composition was normalized after probiotic treatment