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Typical formulations include 50-200mg of glycine per vial
In the SURMOUNT-1 trial, participants taking the highest dose (15 mg) of tirzepatide lost an average of up to 20.9% of their body weight over 72 weeks
While 503B facilities are required to follow current Good Manufacturing Practices (cGMP), the compounded drugs themselves are not FDA-approved. If semaglutide and tirzepatide are removed from the 503B bulks list, the availability of compounded GLP-1s would drop significantly, Michael Snyder, MD, FACS, FASMBS, DABOM, medical director of the Bariatric Surgery Center at Rose Medical Center, founder and director of the Denver Center for Bariatric Surgery Foundation, and in-house obesity specialist at FuturHealth, told MNT
It sits between the 1.0 mg step and the 1.7 mg step on the standard Wegovy escalation schedule, which makes it a moderate dose that many people use during the titration phase