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Furthermore, the H 2 S-producing enzyme, 3-MST, is a mitochondrial enzyme, which accounts principally for renal mitochondrial H 2 S production, while CBS and CSE (cytosolic H 2 S-producing enzymes) translocate to the mitochondria to increase endogenous H 2 S production in response to specific stressful stimuli

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Rigolon JR, Barbosa SS, Goudouris ES

GLP-1 receptor activation stimulates glucose-dependent insulin secretion from pancreatic beta cells, suppresses inappropriate glucagon release, slows gastric emptying, and reduces appetite through central nervous system pathways