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VSMC death causes vascular inflammation, loss of extracellular matrix (ECM) and collagen, weakening of the fibrous cap, and ultimately plaque rupture (Xu X

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Supports cardiovascular health indirectly: Weight loss and glucose regulation together can reduce cardiometabolic risk factors

The Ozempic prescribing information lists three indications, all in type 2 diabetes: glycemic control, reduction of major adverse cardiovascular event risk in adults with established cardiovascular disease, and reduction of the risk of sustained eGFR decline, end-stage kidney disease and cardiovascular death in adults with chronic kidney disease