The activity of LS GLP-1R neurons rapidly decreased during naturalistic feeding episodes, while synaptic inactivation of LS GLP-1R neurons diminished the anorexic effects triggered by liraglutide
doi:10.1097/MD.0000000000035488 53
Cardiovascular Benefits: Studies suggest that GLP-1 medications may help reduce the risk of cardiovascular events, such as heart attacks and strokes, in individuals with type 2 diabetes

[3] The benefits of fiber We'll briefly gloss over the benefits of fiber, but for a more detailed read, the 2020 article recently published in Nutrients titled "The Health Benefits of Dietary Fibre" has a great modern overview, which cites not just standalone studies, but numerous meta-analyses also cited below: [4] Gut motility and constipation prevention [5] Body weight and abdominal body fat improvements [6,7] Insulin sensitivity and overall metabolic health improvements [8] Healthier gut microflora environment [9] Reduced inflammation [10,11] A minor improvement in mood [12] Lower rates of cardiovascular disease [13,14] Reduced risk of colorectal carcinoma [15,16] Lower overall mortality [17] Each of the studies cited above looks at various mechanisms, but most of them seem to be downstream of the fact that fiber helps the gut ferment short-chain fatty acids (SCFAs) , [18,19] which have incredible benefits ranging from anti-inflammatory activity [20] to a heart-protective reduction in TMAO (Trimethylamine-N-oxide)

Methods: A multicenter cohort study was conducted, including patients with biopsy-proven CHB, MASLD, and MASLD combined with CHB from 11 medical centers