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2020ZFB010, and the Foundation of State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers (2025GTEP016)

Weeks 8-12: Body composition changes become visible gradual fat loss (particularly in the midsection) and improved muscle tone

Ethics declarations Competing interests SJW is the founder of Ridgeline Therapeutics, HN is a paid employee of Ridgeline Therapeutics and, since manuscript submission, ADW has also become a paid employee of Ridgeline Therapeutics

TB-500 mimics Thymosin Beta-4 and focuses primarily on cell migration, muscle repair, and inflammation reduction

FO no longer have a financial interest in the company