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posters said they must be on GLP-1s

GLP-1 receptor agonists function by mimicking a hormone that targets areas of the brain involved in appetite regulation

The REWIND trial with dulaglutide included many patients without established ASCVD and demonstrated a consistent reduction in MACE, supporting a role in primary prevention, although the effect size was modest

Patients who carry variants associated with rapid satiety onset often report that evening injections prevent excessive daytime appetite suppression, maintaining normal work-day nutrition

The longer you remain on the drug at an effective dose, the closer you approach the trial maximum