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Declaration of interests F.C.S reports grants from the NIH NDDK, she also reports personal consulting fees from Eli Lilly, Novo Nordisk, Boehringer Ingelheim, Pfizer, Rhythm, Currax, and Gelesis

Substances are often placed in Category 2 due to: Insufficient human safety data Concerns about impurities or manufacturing variability Lack of clinical justification for traditional pharmacy compounding When a substance is in Category 2, traditional 503A compounding pharmacies generally should not compound it

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Citation257 Dosing and Timing: Finding the right dosing schedule for senolytics and senomorphics is critical to their success in clinical practice