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Hyperpigmentation occurs when patches of skin become darker than the surrounding areas, typically due to an excess production of melanin

The fact that initial infections, due to more virulent strains such as the original Wuhan strain and the Alpha variant, are associated with a higher risk of long COVID may be due to an erratic and overwhelmed immune response following SARS-CoV-2

Animal studies show that these medications cause developmental abnormalities in the fetus