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Additionally, tirzepatide slows gastric emptying, which may impact how your body absorbs other oral medications, including weight loss aids, supplements, and hormone therapies

Fatty Acid Oxidation Disorders A deficiency in carnitine or enzymes like carnitine palmitoyltransferase (CPT) can severely impair the bodys ability to break down fatty acids, leading to a reliance on glucose for energy

doi: 10.1016/j.lfs.2017.12.025

Time-restricted eating (limiting food intake to an 8-12 hour window) has shown some metabolic benefits in small studies, but mechanisms are not fully established and may involve multiple hormonal pathways

Gloyn noted that large amounts of genetic data from clinical trials likely already exist and could help answer important questions about why some people respond poorly to GLP-1 therapies