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Comparison of the vehicle-treated normal C57BL/6J mice to vehicle-treated MIA mice showed significantly lower social novelty index scores in the MIA mice, p = 0.0002

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Beyond the typical regulatory pathways mentioned above, ferroptosis is modulated by many regulators, such as p53, nuclear factor erythroid 2-related factor 2 (Nrf2) and AMP-activated protein kinase (AMPK)[37-39], among which p53 gets a lot of attention due to its controversial role in ferroptosis