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In the case of mass spectrometry (MS)- based metabolomics, several strategies are use, e.g., desorption electrospray ionization mass spectrometry (DESI-MS) or flow injection analysis-MS (FIA-MS), or in combination with separation techniques such as gas chromatography-mass spectrometry (GC-MS), liquid chromatography-mass spectrometry (LC-MS), or capillary electrophoresis-MS (CE-MS), to increase separation and better identification and quantitation of the metabolites present in a cell extract (Pitt, 2009

Persistent oxidative stress is closely related to the delayed healing of diabetic wounds, and lipid peroxide accumulation via the circulation further contributes to iron metabolic pathway disruption

The reactive metabolites can irreversibly bind to proteins which lead to direct toxicity by disrupting the cell function

Glycolic acid exfoliates dulling surface cells and enhances vitamin C delivery