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Vitamin B2 deficiency disrupts intermediary metabolism, potentially impairing energy production via the ETC, which is mainly concerned for the nervous system, given its high energy demands, and also can lead to disorders, such as migraine, because of energy failure, alongside overproduction of ROS (, )

Gill, S

the goal is to circumvent chemoresistance by using multiple drugs with different anticancer mechanisms (Doroshow 2017)

That's where having a dietary supplement strategy comes in