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Higher doses (90 mg and 120 mg) achieved up to 12.2% mean reduction from baseline (26.6 lbs) versus 1.3% (2.9 lbs) for placebo, with up to 97% of patients losing 5% of body weight

Mitochondrial dysfunction, apoptosis and oxidative stress are in part due to methylglyoxal accumulation

Plus, it was easy to find help: A company called WhiteLabelMD handles customer service, provides software, and connects patients with clinicians who prescribe drugs like semaglutide and tirzepatide

These medications are manufactured by large pharmaceutical companies and are dispensed at retail pharmacies

Most importantly, it provides advice and tools to aid clinicians in selecting suitable alternatives to GLP-1 RAs where there is limited availability