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Mistake 2: Expecting immediate results Tissue repair is a biological process that takes time

Other studies have demonstrated elevated activities of SOD1 and SOD2 within active demyelinating lesions ( 2 O 2 accumulation and exacerbate OS ( 1 HMRS) studies have further revealed reduced GSH levels in specific brain regions of MS patients ( Beyond classical antioxidant enzymes, dysregulation of multiple OS-related proteins and pathways has been reported in MS, including peroxiredoxin (PRX), an enzyme critical for reducing H 2 O 2 whose dysregulation may impair the cellular ability to handle peroxides ( 2.3 The inflammatory-oxidative axis in MS In MS pathogenesis, the inflammation-driven oxidative burst generated by activated microglia, astrocytes, and infiltrating macrophages play a critical role in demyelination and subsequent injury to neurons, axons, myelin, and oligodendrocytes (Figure 2)

Circulation 118 , 19291937 (2008)

JNCI: J Natl Cancer Instit