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sTNFR1 is currently in clinical use as a biomarker for heart failure

PQQ: An antioxidant that supports the growth of new mitochondria

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Considering that energy metabolism is also able to regulate ROS levels, we supplemented sodium pyruvate (the sodium salt form of pyruvate, a key energy substrate for cellular metabolism) or JX06 (a compound that modulates pyruvate flux into the tricarboxylic acid cycle) in GGCT-knockdown cells, respectively