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Heres a look at the common side effects of semaglutide : The serious side effects that can occur when taking either form of semaglutide include : Pancreatitis Diabetic retinopathy complications Hypoglycemia (low blood sugar) Acute kidney injury Allergic reactions Acute gallbladder disease Pulmonary aspiration during general anesthesia or deep sedation Similar to Saxenda, Wegovy also includes an increase in heart rate and suicidal behavior or ideation in its list of possible serious side effects