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An analog of MC4-NN2-0453 (MC4-NN1-0182) demonstrated similar food intake decreases in DIO rats and minipigs at 0.3 mg/kg SC, resulting in 7% and 13% loss in body weight, respectively (56)

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Jones J, Jaramillo-Merchan J, Bueno C, Pastor D, Viso-Leon M, Martinez S

xCT and other amino acid transporters, such as L-type amino acid transporter 1 (LAT1) and LAT2, are potential therapeutic targets due to their availability and pharmacological properties

Because of their ability to influence various biological functions, peptides are used in therapeutic treatments, including skin rejuvenation, muscle growth, fat loss, and even cognitive enhancement