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Always refer to the Wegovy Patient Information Leaflet for device-specific instructions on administration, storage, and permitted injection sites

Dipeptidyl peptidase 4 inhibition stimulates distal tubular natriuresis and increases in circulating SDF-11-67 in patients with type 2 diabetes

Decisions should be individualized based on the patient's overall health status, diabetes control, and goals of care

On one hand, it means there is a large, internally consistent literature describing the compounds, their proposed mechanisms, and clinical experience

Just as in lipodystrophic syndromes, genetic or acquired conditions characterized by partial or generalized loss of fat, the progressive inability to accumulate excess calories leads to fat accumulation in ectopic sites (liver, pancreas, heart, etc.)