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In an HG environment, 100 nM/500 nM 25-hydroxyvitamin D3 has been observed to exert a stimulatory effect on the proliferation of HRMECs, accompanied by an augmentation in GSH, SLC7A11, and GPX4

One of the interesting factors in ferroptosis regulation in SCD is through heme oxygenase 1 (Hmox1), which cleaves heme to form biliverdin and thus plays a protective role in vascular function 42,43,44,45