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However, the next phase of translational research must now broaden its scope

Beyond weight loss, GLP-1s seem to tackle conditions right across the body

Alpha-2 agonists may be of benefit in those with ADHD who experience more anger, aggression, or impulsive rage with a stimulant

The authors conclude that the renal benefits cannot solely be explained by weight reduction or risk factor reduction, although these may contribute, and the mechanisms of kidney protection are likely to be multifactorial and may include decreased oxidative stress, inflammation and fibrosis in the kidney

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