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Ferroptosis triggers can be divided into those that act through the cystine/glutamate antiporter system, such as erastin, and those that act by inhibiting the activity of glutathione peroxidase, such as Ras Selective Lethal 3 [73, 74]

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Researchers studying LM22A-4 should note that it is most commonly delivered intranasally in animal models, bypassing the blood-brain barrier through the olfactory pathway