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10.2 Nutritional deficiencies and skin manifestations in ketogenic interventions Nutritional deficiencies also negatively affect the appearance of the skin, often causing a number of severe skin conditions (240)

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Opioid and alcohol withdrawal Clonidine and other alpha-2 agonists lessen symptoms of autonomic hyperactivity associated with opioid and alcohol withdrawal, including sweating, diarrhea, intestinal cramps, nausea, anxiety, and irritability (Gold et al, 1978

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