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Tambin afecta el funcionamiento del msculo cardiaco, incrementando el riesgo de insuficiencia

Linus Pauling Institute Oregon State University Updated in July 2013 by: Barbara Delage, Ph.D

Why the Changes Were Made The updates follow: A TGA safety review incorporating DAEN data ACM consultation in June 2025 International regulatory assessments Evidence on tirzepatides effects on gastric emptying The need to harmonize previously inconsistent PI/CMI statements across different GLP-1 products TGA emphasizes that these updates do not change the approval status or availability of these medicines, but ensure clearer and more consistent risk communication

Authors contributions BG, JCL, and LAV participated in the concept and drafting of the manuscript, and performed the critical review for intellectual content

All had heart failure with preserved ejection fraction (HFpEF), the most common form of the condition