Children NAC has been used safely in children and adolescents at doses of 6002400 mg per day in a number of clinical trials, 78,94,95,105 although one RCT in autistic children reported constipation (16.1%), increased appetite (16.1%), fatigue (12.9%), nervousness (12.9%) and daytime drowsiness (12.9%), which occurred significantly more commonly in the NAC than in the placebo group
However, it has been structurally modified to bind to albumin in the bloodstream, which dramatically extends its half-life to approximately six to eight days (with DAC formulation)
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This is exactly where the characterisation by Raun et al., 1998 applies: ipamorelin achieved a GH release comparable to GHRP-6 without raising ACTH, cortisol or prolactin above the GHRH level
DO NOT USE ON CUTS, WOUNDS OR OTHER OPEN AREAS OF SKIN