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Based on the outcome of the BLOOM (46) and BLOSSOM trials (47), in 2012 the FDA approved lorcaserin as an addition to a reduced-calorie diet and exercise for eligible patients (48)

Some researchers suggest metabolic shifts as the body adjusts to altered fat metabolism could trigger them

This therapy is not recommended for individuals who are pregnant, breastfeeding, or taking antidepressants such as SSRIs or MAOIs