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A friendly reminder that while calorie restriction can achieve short-term reductions in weight ( 12 months)

Animal studies have also shown that portal vein GLP-1 weakens intestinal fat absorption and chylomicron production through the vagal enteric-brain-liver axis, and reduces postprandish and fasting blood lipids [79]

Berberine activates AMPK, which is the same pathway that gets activated during exercise

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