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If patients have a history of type 2 diabetes mellitus, tobacco use, or advanced chronic kidney disease, then they may be at an increased risk of developing acute pancreatitis, a serious and potentially life-threatening condition, after being started on a GLP-1 receptor agonist for the goal of weight loss

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Effect sizes were interpreted using Cohens benchmarks: small (0.2), moderate (0.5), and large (0.8) (Muller, 1989)

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Some people also benefit from methylation testing to understand how their liver processes nutrients and medications