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Limitations: Do not contain cytosolic enzymes (e.g., sulfotransferases, glutathione S-transferases) or phase II conjugating enzymes (UGTs), unless supplemented with UDPGA

PlexusDx offers this $99 genetic test as an add-on after your first month of treatment, enabling data-driven personalization

Your doctor may need to adjust the dosage of your other medications to minimize this risk

The clearest answer to date comes from a Phase 2 trial published in the New England Journal of Medicine in 2023, which reported 24.2% weight loss after 48 weeks at the highest dose in 338 adults with obesity but no other complications

DM This story was first published in The Conversation