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The development of targeted therapies must consider the potential off-target effects on normal tissues that rely on EMP, necessitating a careful balance between therapeutic efficacy and safety

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LC216 is studied most frequently in hepatocyte cell culture models, in vitro lipid metabolism assays, and rodent-based metabolic syndrome protocols

The studys second phase will follow participants for up to five years to gather data on semaglutides impact on long-term liver complications

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