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Store reconstituted dihexa solutions at 28C and use within 14 days to minimize degradation and precipitation risk

This stimulates the release of growth hormone (GH) and subsequently increases insulin-like growth factor 1 (IGF-1) without suppressing endogenous GH production

Given that species-specific differences have been reported for other multi-agonists such as tirzepatide [35], further studies using human islets are warranted to confirm the involvement of GLP-1R and the GqTRPM5 signalling axis in humans

Dispose of the used syringe immediately in your sharps container

Then the absorbance at 450 nm was measured with 600 nm as the reference wavelength