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The different CRP isoforms, nCRP, non-native pentameric CRP (nnCRP) and mCRP (175178, 181184), may explain their protective and destructive effects, with nCRP being primarily antiinflammatory inducing Th2/M2 responses, while mCRP being typically proinflammatory inducing Th1/M1 responses (170, 185189)

doi: 10.1016/j.redox.2022.102292 180 WuMYYiangGTLaiTTLiCJ

Subsequently, the stained samples were mounted on microscope slides and visualized under a fluorescence microscope (Zeiss Axio Imager M2, Carl Zeiss Microscopy GmbH, Jena, Germany) equipped with UV excitation at 365 nm

If its not expressing, youre fine

All the members form heterodimers with small Maf proteins through leucine zipper motifs and bind to the ARE consensus sequence through basic regions, suggesting that the bZip structure of Nrf2 shares many common properties with that of other CNC members