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One molecule, called IP, moves into the fluid inside the cell and may ultimately bind to channels on internal calcium stores, causing Ca to be released into the cytoplasm

Each woman with PCOS can have a different hormonal pattern and root causes, requiring a personalized treatment strategy

Weight loss during this period is typically 2 to 4 pounds, primarily from reduced caloric intake and initial fluid shifts

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The medication is initiated at a low dose (0.25 mg) and gradually increased over 16 weeks to the maintenance dose of 2.4 mg to minimise gastrointestinal side effects, which are common during the early stages of treatment