This effect is relevant not only in neurodegenerative pathology but also in aging, where brain inflammation is chronically elevated ( In prior studies, the antioxidant, anti-inflammatory, and anti-apoptotic properties of AST have been reported to improve the quality of life in diseases ranging from cancer to neurodegenerative diseases
The quality of the extract matters a lot here: Good extracts contain 50-90% catechins while lower quality ones are mostly there for marketing

Hippophae Rhamnoides Water, Water, Diisopropyl Sebacate, Titanium Dioxide (CI 77891), Propanediol, Butylene Glycol, Butyloctyl Salicylate, Dibutyl Adipate, Ethylhexyl Triazone, Terephthalylidene Dicamphor Sulfonic Acid, Niacinamide, Alcohol Denat., 1,2-Hexanediol, Tromethamine, Dimethicone, Hippophae Rhamnoides Oil, Caprylyl Methicone, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Polymethylsilsesquioxane, Polysilicone-15, Isododecane, Octyldodecanol, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Pentylene Glycol, VP/Eicosene Copolymer, Polyglyceryl-3 Distearate, Potassium Cetyl Phosphate, Cetearyl Alcohol, Glyceryl Stearate, Dimethicone/Vinyl Dimethicone Crosspolymer, Polyglyceryl-4 Isostearate, Hydroxyacetophenone, Methylpropanediol, Polyester-5, Isopropyl Titanium Trisostearate, Aluminum Hydroxide, Polyglyceryl-10 Myristate, Carbomer, Glyceryl Stearate Citrate, Adenosine, Hydroxypropyl Methylcellulose Stearoxy Ether, Sodium Polyacryloyldimethyl Taurate, Xanthan Gum, Glutathione, Polyether-1, Cetyl Hydroxyethylcellulose, Ethylhexylglycerin, Xyloglucan, Arginine, Alpha-Arbutin, Ascorbic Acid, Cyanocobalamin, Panthenol, Tocopherol, Ubiquinone, Hydroxypropyl Cyclodextrin, Glycerin, Polyglyceryl-10 Laurate, Thioctic Acid, Hydrogenated Lecithin, Tremella Fuciformis (Mushroom) Extract, Potassium Hydroxide

Old strains or untreated acute tendonitis often lead to chronic inflammation
doi:10.1073/pnas.12.2.132