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Endocrine 48(1):107115 Chai S, Liu F, Yang Z, Yu S, Liu Z, Yang Q, Sun F (2022) Risk of fracture with dipeptidyl peptidase-4 inhibitors, glucagon-like peptide-1 receptor agonists, or sodium-glucose cotransporter-2 inhibitors in patients with type 2 diabetes mellitus: a systematic review and network meta-analysis combining 177 randomized controlled trials with a median follow-up of 26 weeks

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And autophagy acts as an immune system stimulator by controlling immune responses and helping to rejuvenate the immune systems cells