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5.1 Anti-inflammatory and anti-nociceptive effects Omega-3 and omega-6 polyunsaturated fatty acids (PUFAs) play distinct roles in inflammation, with omega-3 PUFAs generally exhibiting anti-inflammatory effects and omega-6 PUFAs tending towards pro-inflammatory actions, through competitive metabolic processes

Vitamin C maintains glutathione in its active reduced state (GSH) and works synergistically as an antioxidant

10.1016/j.mam.2012.05.003 Mol

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[17] From 1981 to 1983 Beutler continued his medical training at the University of Texas Southwestern Medical Center in Dallas, Texas, as an intern in the Department of Internal Medicine, and as a resident in the Department of Neurology