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"The medication might be degraded faster in one individual than in another," she says, which might also explain the different responses to GLP-1s

Females and Males of Reproductive Potential Inform female patients that treatment with metformin may result in an unintended pregnancy in some premenopausal anovulatory females due to its effect on ovulation [see Use in Specific Populations (8.3)]

Phentermine's FDA approval covers short-term use, typically 12 weeks or fewer, and reflects decades of evidence focused on acute appetite suppression