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The RMSD of juglone with respect to the ChaC1 protein was found to be as high as 60 (Figure 9 A grey dotted line)

PARP cleavage inhibition: PARP, a downstream target of caspase-3, saw its cleavage fragments reduced by 77.5%

Concussion is characterized by a metabolic cascade where ions and metabolites are in a dynamic flux 5 , suggesting neurochemistry has the potential to be disturbed following concussion 5,6,7,8,9