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doi: 10.1111/cen.13003

These improvements occurred across multiple study populations regardless of whether participants intentionally restricted calories beyond what the time window naturally imposed

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A quantitative pharmacology approach (QP-A) and model-based drug development (MBDD) offer a promising method to select promising compounds early and streamline the development process

Very lean patients may benefit from pinching the skin to create a subcutaneous 'tent' or using a 45-degree angle to avoid intramuscular injection