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At 6 months, significant reductions in AST, ALT, and GGT levels were observed in both treatment groups

The group of wild-type mice treated with hepsin and a reduced dose of 200 mg/kg NAC exhibited significantly lower levels of both enzymes, indicating reduced liver damage compared to the other groups (Fig

This inflammation can be life-threatening and patients who experience these symptoms are urged to seek medical care

IWQOL-Lite (Impact of Weight on Quality of Life): +25 points with retatrutide vs +5 points with placebo a 20-point additional improvement in weight-related quality of life

Additionally, emerging data indicate crosstalk between the liver and -cells mediated by hepatokines and extracellular vesicles ( 4.6 Translational considerations While mouse models provide essential mechanistic insights, species-specific differences in lipid metabolism and inflammatory responses must be considered