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In mammals, G6PD is a good example of a housekeeping enzyme produced by a housekeeping gene

The evidence reveals three distinct outcome patterns: disease improvement, stable disease with weight loss, or transient GI symptom exacerbation requiring dose adjustment or medication change

Given the pronounced effect of tau elimination observed in in vitro and in vivo studies, selecting patients who test positive for tau biomarkers (CSF, blood, or positron emission tomography) could enhance the likelihood of achieving significant disease modification

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The "without DAC" version is gone in about 30 minutes