In this same study, the authors could point out that the most overrepresented protein in the secretome of such cells was cathepsin F and that this was driven by the accumulation of not Gb3, but of LIMP-2, a lysosomal protein with suggested role in heart disease [80]
Over a week, that is 2100 to 3500 extra calories, enough to fully offset the calorie deficit tirzepatide created
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