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Some peptides occur naturally (like growth hormone-releasing peptides), while others are synthetically developed for research or medical purposes

Animal studies involving both GH-deficient and non-GH-deficient mice have shown that twice-daily ipamorelin injections lead to significant increases in body weight (15.3% and 16.9% respectively) [8] and stimulate GH secretion, which is lipolytic [9]

For dogs, the standard dosage is 50 mg per kg of body weight, twice a day

But claims that peptides can improve brain fog and increase mental clarity are mostly marketing, says Nadolsky

At these amounts, it's considered non-irritating and non-sensitizing based on repeat-use patch testing