[Abstract]2025 Apr 28:235:150-161
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By showing that rats pretreated with a dopamine-synthesis inhibitor show less toxicity in response to methamphetamine than non-treated rats, this study was one of the first to suggest that dopamine is involved in the neurotoxic actions of this psychostimulant
In addition, exenatide was shown to activate GLP-1R and inhibit the PI3K/AKT pathway to inhibit the growth, migration, and invasion of ovarian cancer cells, and promote cell apoptosis, thereby producing anticancer effects on diabetic patients with ovarian cancer (218)
It mimics the pulsatile rhythm of natural growth hormone and gives the pituitary axis a recovery window twice a week