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BPC-157 has demonstrated no significant toxicity across numerous rodent studies even at high doses (Sikiric et al.), with no reported hepatotoxicity, no cardiovascular signal, and no reported dependence

The agency also warned that it was likely the problems were underreported

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Abstract Aim We hypothesized that certain effects of the general anaesthetic thiopental are dependent on NO-related mechanisms, which were consequently counteracted by stable gastric pentadecapeptide BPC 157