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PLoS ONE 8:e61965

Telogen effluvium: A form of diffuse shedding that occurs when many hairs enter the resting phase at once, often after stress or rapid weight loss

While it is not FDA-approved, clinicians and patients alike are watching it closely because it represents a new direction in peptide therapy for weight loss where its triple-agonist mechanism is something that many did not expect

One study, EMPA-KIDNEY, was more broadly based, and included people who were minimally proteinuric (ACR 65 years, glycated hemoglobin (A1C) 7%, baseline eGFR 30 mL/min per 1.73 m, or uACR 30 mg/mmol [72]

The mean absolute bioavailability of Tirzepatide following subcutaneous administration is 80% (source)