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They concluded that melatonin and vitamin C treatment protected against citalopram-induced testicular injury by modulating nitrooxidative stress and apoptosis (Figure 1)

As expected, this includes facilitating chromatin accessibility, for instance by SWI-SNF proteins, and histone modifications that contribute to this, for instance those exerted by histone acetylases and deacetylases, such as p300 and HDAC3, respectively

Kozina LS, Arutjunyan AV, Khavinson VKh