Similarly, another meta-analysis of 5 cardiovascular outcome trials reported no significant effect of GLP-1RAs treatment on ventricular fibrillation in T2DM patients [13]
Abstract Background Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have recently received Food and Drug Administration (FDA) approval for obesity management
While nausea, vomiting, and diarrhea are the most commonly reported gastrointestinal adverse effects with GLP-1-based therapies (occurring in 15-40% of patients depending on the agent and dose), FDA prescribing information for several of these medications does list dyspepsia (indigestion) and, in some cases, gastroesophageal reflux disease (GERD) as reported adverse reactions
References National Center for Biotechnology Information
PubMed CrossRef Arans C, Edvardsson CE, Shevchouk OT, et al