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Depressive symptoms, measured using the CES-D, were considered suggestive of having depression if the total score was 16 out of 60 (83, 84)

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A loss-of-function shRNA targeted screen in metastatic-derived cells identified Gstt1 , a member of the glutathione S -transferase superfamily, as uniquely required for dissemination and metastasis, but dispensable for primary tumour growth